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A frequent prescription drug for moderate-to-severe pain relief is Vicodin. It combines acetaminophen, a non-opioid analgesic and fever reducer, with hydrocodone, an opioid painkiller. Acetaminophen amplifies the effects of hydrocodone and serves to lower fever, while the former acts by changing how the brain and nervous system react to pain.
Vicodin is normally taken orally as tablets, with dosages recommended based on the patient's health and the degree of pain. Because hydrocodone has the potential to be abused and cause dependence, it is only meant to be used temporarily.

Vicodin frequently causes nausea, constipation, dizziness, and sleepiness as adverse effects. If overused, more serious adverse effects like disorientation and short breathing may happen.